Research and professional experience
1985 - 1987 Molecular Human Genetics, Res. Assistant, Acad. of Sciences, Berlin, GDR
1987 - 1990 Dep. of Human Genetics, non-tenured employee, Humboldt-Univ.Berlin, GDR
1990 - 1992 Research Associate, University of British Columbia, Vancouver, Canada
1992 - 1999 Molec. Human Genetics, Senior Scientist, Ruhr-University Bochum, Germany
1999 – 2001 Associate Professor (C3), Head of the Department of Medical Genetics, University of Rostock, Germany
Since 9/2001 Full Professor (C4) of Medical Genetics, Director of the Department of Medical Genetics and of the Institute of Human Genetics, University of Tübingen
2007 – 2010 Dean of Research of the Medical Faculty of Tübingen, Germany
2010 - 2014 Dean of International Affairs of the Medical Faculty of Tübingen, Germany
Since 2010 Director of the Center of Rare Diseases Tübingen
Since 2014 Founding member of the Center of Personalized Medicine, University of Tübingen
Since 2018 Coordinator of the DFG funded German NGS facility NCCT

Memberships and Positions
2005 -2009 Member of the scientific board of the German Society of Human Genetics
2005 -2007 Board member of the study section Neuroscience (Fachgutachter) of the German Research Foundation
Since 2007 Member of the scientific board of the Comprehensive Cancer Center Tübingen
2008 -2010 Vice President of the German Society of Human Genetics
Since 2009 Founding member and President of the “Research and treatment center of rare diseases Tübingen” (First German Center on Rare Diseases)
Since 2009 Member of the task force on a national plan for rare diseases of the German Ministry of Health (BfG, NAMSE)
2011-2014 Member of the Senate of the EK-University Tübingen (Senator)
2012-2016 Board member of the study section Neuroscience (Fachgutachter) of the German Research Foundation
2012 Associated Member of the Commission on genetic diagnostics (Gendiagnostik-Kommission) of the Ministry of Health (BfG)
2013 Board member of the International Rare Disease Research Consortium IRDiRC (Diagnostics Scientific Committee)
2015-2018 President-elect/President/Vice-President of the European Society of Human Genetics (ESHG)
Since 2017 Member of the “Unsolved” Task Force of IRDiRC
Since 2018 UDNI Board of Directors (Undiagnosed Disease Network Initiative)
Since 2018 ESHG board member
Since 2019 Member of the Senat of the University of Tübingen (Senator)
Since 2020 Advisory board of the German Ministry of Health on genomDE
Since 2020 Advisory board of the German Ministry of Health in the European consortium 1+MEGA on Rare Diseases
Since 06/21 President of the German Society of Human Genetics (GfH)